IGF-1 LR3

Product Overview Long R3 Insulin-like Growth Factor-I (IGF-1 LR3) is a highly modified, synthetic analogue of human IGF-1. Designed specifically for enhanced stability and prolonged biological activity, it features an 83-amino acid sequence with an arginine substitution at position 3 and a 13-amino acid extension at the N-terminus. Enhanced Bioavailability: The structural modifications prevent IGF-1 LR3 from binding to IGF-binding proteins (IGFBPs), vastly increasing its half-life and potency in cell cultures compared to native IGF-1. Cellular Research: Extensively used to study cellular hyperplasia (cell division), differentiation, and survival across various tissue models, particularly skeletal muscle. Research Applications In vitro stimulation of myoblast proliferation and differentiation. Media supplement for serum-free cell culture environments. Studies mapping the PI3K/AKT and MAPK signaling pathways. Specifications Format: Lyophilized powder Purity: >98% (HPLC/MS verified) Storage: Store reconstituted solutions at 4°C for short term, or aliquot and freeze at -20°C for long term. RESEARCH USE ONLY. This product is strictly for laboratory research and development purposes. It is NOT for human consumption, diagnostic, therapeutic, or clinical use.